Mitochondria waxay qabataa wax ka badan in ay awood siiso unugyada.
Waqtiga akhriska ee la qiyaasay: 9 daqiiqo
Ha i fahmin. Waxay leeyihiin wax kasta oo ay ku sameeyaan tamar. Iyo sababta oo ah waxay aad muhiim ugu yihiin wax soo saarka tamarta, waxay door muhiim ah ka ciyaaraan dheef-shiid kiimikaadka. Natiijo ahaan, waxay udub dhexaad u yihiin goobta Cilmi-nafsiga Metabolic.
Waxaan maqalnaa in mitochondria ay yihiin awoodaha unugga gabi ahaanba meel kasta. Ama ugu yaraan waxaan ku sameeyaa wareegyada aan ku dhex jiro. Oo waxaad arki doontaa in lagu sheegay dhammaan qoraallada blog-ka ee boggan. Xidhiidhinta in mitochondria ay yihiin xarumaha awoodda ee unugyadaada runtii waa habka ugu fudud uguna fudud ee laguula soo xiriiro oo aad uga baahan tahay tamarta neerfaha. Way fududahay in la fahmo. Haddii aynaan ku haysan baytari shaqaynaysa toosh, tooshku ma shaqayn doono. Oo haddii baytariyadayadu dhimanayaan, waxay noqon doontaa nooc shaqaynaysa, laakiin aad uma fiicna. Taasina waxay u socotaa maskaxdeena marka aan qabno cilladda mitochondrial ee socota. Unugyadu ma qaban karaan shaqada faraha badan ee ay u baahan yihiin inay qabtaan si ay si sax ah kuugu socoto.
Laakin kuwa idinka mid ah oo doonaya in ay wax badan ogaadaan, waxaa muhiim ah in la ogaado in mitochondria ay aad uga badan tahay awoodaha unugyadiina. Markaa danta faham yar oo dhammaystiran oo ku saabsan waxa xubnahan yaryar ee sixirka ah ay sameeyaan ayaan u qoray bartan blog!
Fiiro gaar ah: Uma isticmaalo ereyga sixir si fudud. Haddii aadan jeclayn ereyga sixir, si kastaba ha ahaatee, ku beddel ereyga quantum. Sababtoo ah taasi sidoo kale waa sax oo quruxsan darn qabow. Laakiin ka baxsan baaxadda maqaalkan yar (I am no physicist).
Mitochondria waxay u tarjumaysaa inta u dhaxaysa adduunka tirada iyo makroscopic iyo Isticmaal tunnelka quantum ee elektarooniga si loo yareeyo carqaladaha tamarta firfircoonida socodka elektaroonigga ah. Tunnelka korantada ayaa si weyn loogu asteeyay Complex I ee silsiladda gaadiidka elektaroonigga ah.
Bennett, JP (2019). Mala-awaal caafimaad: Cudurrada neerfayaasha ayaa ka soo baxa dhaawaca oksaydhiyaha ee borotiinnada tunnelka elektarooniga ah ee mitochondria. Mala -awaal caafimaad, 127, 1-4.
Haddaba aynu gudaha u galno waxyaalaha kale ee mitochondria ay ka ciyaarto door muhiim ah oo aan ka ahayn wax soo saarka tamarta cajiibka ah. Haddii aad rajaynaysay maqaal mitochondria gaar ah cuntooyinka ketogenic, waxaad tahay nasiib. Waayo mid ayaan qoray. Waxaad ka heli kartaa halkan:
Jawaabta cadaadiska
Waxa jira culaysyo jidheed iyo walbahaar maskaxeed. Awooda jidhkaagu u leeyahay in uu wax ka qabto walbahaarka nooc kasta ha ahaadee waxa ay hoos ugu dhacdaa shaqada mitochondrial. Ma la kulantay fayras ama bakteeriyo culays saaraysa habka difaacaaga? Mitochondria ayaa nidaamisa shaqada habka difaacaaga. Ma la tacaalaysaa walaac nafsiyeed oo noloshaada kugu adag? Mitochondria ayaa mas'uul ka ah awoodda unuggaaga si uu ula qabsado, u noolaado oo u noqdo mid adkeysi leh isagoo bilaabaya isbeddellada muujinta hidda-socodka iyo dheef-shiid kiimikaadka labadaba. Haddii aadan lahayn mitochondria caafimaad qaba oo badan si aad u taageerto unugyada markaa unugyo badan ayaa dhimanaya, ama ka sii daran. Waxay isu beddelaan zombies (senecence) kuwaas oo soo saara qaar ka mid ah calaamadaha caabuqa xun ee kordhiya cadaadiska oksaydhka oo ka sii dara calaamadahaaga.
Soosaarka hormoonka
Haddii ay tahay unug sameeya hormoonnada, waa unug u baahan tamar ka badan inta badan taas macnaheedu waa mitochondria ayaa asal ahaan mas'uul ka ah isku-darka hormoonnada. Waa sax. Hormoonnada sterol sida estrogen, testosterone, iyo cortisol. Mitochondria ayaa haya furaha. Isla markiiba si loo bixiyo enzymes loo baahan yahay si loo bilaabo wax soo saarka hoormoonka.
Tani waa sababta daawayntaada shaqaynaysa ee daalka adrenal aanay shaqaynayn. In lagu siiyo sterols dhirta si aad u bedesho cortisol kaaga kama hadlayso cillad la'aanta mitochondrial ee socota. Tani waa sababta daaweynta beddelka hormoonka aysan dhab ahaantii ahayn faragelin "sabab asal ah". Haddii hormoonnadaadu ay ka baxeen fir-fircooni, waa calaamad muujinaysa cilladda mitochondrial. Ujeedada faragelinta ayaa ah in la wanaajiyo shaqadaada mitochondrial.
U sheeg asxaabtaada.
Nadiifinta qashinka
Ku dhowaad maqaal kasta oo ku yaal boggan wuxuu ka hadlayaa doorka diiqada oksaydhiyuhu ku leeyahay cudurrada dhimirka iyo xanuunka neerfaha. Cadaadiska Oxidative waa waxa aan ugu yeerno culeyska isku dayga ah in la hagaajiyo dhaawaca ka yimaada Noocyada Ogsajiinta Reactive (ROS). Marka mitochondria-gaagu uu badan yahay oo uu caafimaad qabo waxaad guud ahaan haysataa dhammaan caawimada aad u baahan tahay si aad u hagaajiso heerka caadiga ah ee waxyeelada ka timaadda nolosha iyo socodka adduunka.
…mitochondria waxay u adeegtaa sidii ilaaliyayaal ROS ah.
(Palmer, 2022, bogga 126)
Mitochondria badan oo si fiican u shaqeysa ayaa loo baahan yahay si loo ilaaliyo cadaadiska oksaydhiyaha. Iyo ilaalinta diiqada oksaydhka ee hubinta ayaa loo baahan yahay si loo helo maskax shaqaynaysa. Cadaadiska Oxidative ee aan la hubin waxay keenaysaa hababka neurodegenerative ee saameeya niyadda iyo shaqada garashada. Mitochondria Waxay yihiin qalab shaqada iyo dayactirka hababka antioxidant ee jirkaaga gudaha. Iyo sida aan si isdaba joog ah u sheegay dhammaan maqaallada blog-ka, ma aad isticmaali doontid Vitamin C, turmeric, ama curcumin si aad uga baxdo culeyska cadaadiska oksaydhka ee ka imanaya si liidata ama tirada mitochondria oo aan ku filnayn.
Weydii tiro kasta oo dad ah oo qaadanaya qiyaaso waaweyn oo antioxidants ah marka loo eego talooyinka dhaqtarkooda daawadooda ee wali la halgamaya inay dareemaan wanaag.
U sheeg asxaabtaada qaybtaas, sidoo kale.
Haddii aad wali wax yar ku wareersan tahay farqiga u dhexeeya cadaadiska oksaydhka iyo xanuunka neuroinflammation iyo sida ay u xidhiidhsan yihiin, waxaad ka eegi kartaa maqaalkan hoose:
Laakin mitochondria aad ayey uga badan tahay shaqaalaha nadiifinta marka ay rabshadu dhacdo. Waxay ka caawiyaan ilaalinta unugyada siyaalo kala duwan. Waxay nidaamiyaan tirada unugyada la abuuray, waxay gacan ka geystaan xakameynta waxa isku-xiryada ah ee la jarayo iyo kuwa sii joogaya, waxayna qalab u yihiin habka dib-u-warshadaynta taas oo ah qayb ka mid ah shaqada unugyada caafimaadka leh (autophagy, apoptosis cell - nooca wanaagsan ee dhimashada unugyada). Ma aha oo kaliya nadiifinta qashinka ka dib markay dhacaan. Mitochondria ayaa hubinaya muujinta hidda-wadaha caafimaadka qaba iyo shaqada unugga si loo yareeyo suurtagalnimada in qas weyn uu ku dhaco meesha ugu horeysa.
Xarafka Gene
Xariiqda ugu hooseysa halkan waa hiddo-wadahaagu si sax ah isuma sheegi doonaan haddii aysan jirin mitochondria oo shaqaynaysa. Qiyaastii 20 sano ka hor waxay ogaadeen in mitochondria loo baahan yahay si loo qaado borotiin ka caawiyay nidaaminta muujinta hidda-socodka. Mitochondria waxay leeyihiin DNA u gaar ah iyo koodka DNA-da ee borotiinada nidaamiya muujinta hidda-wadaha. Iyo muujinta hidde-sidaha ayaa saameyn ku leh jawaabaha walaaca, dheef-shiid kiimikaadka, iyo shaqada antioxidant. Marka cilmi-baarayaashu ay la ciyaaraan mitochondria iyaga oo si dhab ah u jebiya (yareynaya awooddooda shaqo) waxay ogaadaan in dhibaatooyin badan oo epigenetic ah ay dhacaan.
Taasi micneheedu waa maxay?
Waxay la macno tahay haddii aadan rabin in hiddo-wadahaaga ay isu muujiyaan siyaalo madadaalo leh oo keena dhibaatooyin iyo calaamado kaa dhigaya (iyo maskaxdaada) da'da degdega ah, waxaad si fiican u saartaa inaad diirada saarto sidii aad u yeelan lahayd laad-dameer caafimaad leh, iyo mitochondria faraxsan.
Haddii aad rajaynaysay inaad si ka sii fiican u fahamto sida ketones u saameeya muujinta hidda-wadaha, waxaa laga yaabaa inaad jeceshahay maqaalkan aan halkan ku qoray:
Neurotransmitter Synthesis
Mitochondria waxay jecel yihiin inay ku noolaadaan synapses. Haddii mitochondria-gaagu uu tiro yar yahay ama ay wax ka hor istaagaan awooddooda inay u safraan meesha loo baahan yahay, markaa ma samaynaysid neurotransmitters-kaaga. Oo haddii mitochondria-gaagu uu tiro yar yahay ama tamar la'aan yahay ama jiran yahay markaas neurotransmitters waxay noqon karaan isku dheelitirnaan.
Iyo neurotransmitters-ka dheellitiran waxay u horseedaan dhibaatooyinka niyadda oo keliya laakiin dhibaatooyinka garashada, sidoo kale. Waxaad u baahan tahay mitochondria caafimaad leh oo badan si aad u abuurto, u sii dayso, oo aad dib ugu qaadato neerfayaashaada ka dibna soo saarto enzymes-ka burburiya. Waan ogahay in aan dhammaanteen u maleyneyno in fikradda ay tahay in neurotransmitters-kaaga ay ku sii jiraan synapses muddo dheer, laakiin taasi waxay keeni kartaa dhibaatooyinkeeda marka aan la jebin karin.
Waa loop jawaab celin ah. Neurotransmitters-ka ayaa soo saaray oo laga faa'iidaystay ka dibna waxay siinayaa mitochondria farriimo muhiim ah oo loo isticmaalo in lagu wanaajiyo shaqada maskaxdaada. Ma jiro qof u xididaya shaqada maskaxdaada sida kuwa xoogga leh, saaxiibada mitirka yar. Yaa ku faraxsan hanashada niyaddaada? Yaa raba inaad dareento caqli, xaadir, iyo karti?
Waa mitochondria kaaga.
Dhakhaatiirta cilminafsiyeedka ee isticmaalaya ugu horrayn daawooyinka si ay isugu dayaan in ay kordhiyaan ama yareeyaan neurotransmitters gaar ah iyaga oo aan tixgelinaynin caafimaadka mitochondrial, waxaan kugu dhiirigelinayaa inaad sahamiso qaar ka mid ah fursadaha tababarka dhimirka ee dheef-shiid kiimikaadka ee lagu bixiyo bogga hoose.
Ugu Dambeyn
Haddii aadan diiradda saarin aag kale oo ka mid ah shaqada soo kabashadaada oo aan ahayn shaqada mitochondrial, waxaad naftaada u samaynaysaa adeeg fantastik ah. Waxaa jira habab aad u fiican oo lagu wanaajiyo shaqada mitochondrial, iyo mid ka mid ah waxqabadyada ugu awoodda badan ee kordhinta tirada mitochondrial iyo hagaajinta shaqada mitochondrial waxay ka kooban tahay cunto ketogenic ah.
Waa maxay sababtu? Sababtoo ah cuntooyinka ketogenic waxay kordhiyaan tirada mitochondria waxayna wanaajiyaan caafimaadka iyo shaqada mitochondria. Cuntada ketogenic waa faragelin mitochondrial ah oo saameeya dheef-shiid kiimikaad iyo dhammaan hawlaha kale ee muhiimka ah ee muhiimka u ah shaqada maskaxda ee lagu qeexay maqaalkan gaaban.
Hoos waxaa ku yaal maqaallo ka hadlaya sababta cuntooyinka ketogenic, iyo kor u qaadista mitochondria ee ka soo baxda, waa daaweyn cajiib ah oo loogu talagalay baaritaanno kala duwan.
Haddii aadan arkin cilad-sheegashada aad xiisaynayso inaad wax ka akhrido, kaliya hoos ugu dhaadhac barta raadinta ee hoose ee bogga!
Hadda oo aad fikrad fiican ka haysato qaar ka mid ah shaqooyinka mitochondria ay bixiso, waxaad ku jirtaa meel aad uga wanaagsan inaad ku raaxaysato qoraallada blog-ka ee boggan.
Haddii aad jeclaan lahayd inaad sahamiso barnaamijka khadka tooska ah ee safarkaaga si aad u barato dhammaan siyaabaha aad u fiicnaan karto, waxaan kugu dhiirigelinayaa inaad wax badan ka barato Barnaamijka Soo kabashada Maskaxda.
tixraacyada
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