Cuntada Ketogenic waxay daaweysaa khamriga

Cuntada Ketogenic waxay daaweysaa khamriga

Cuntada ketogenic ma loo isticmaali karaa sidii daaweyn wax ku ool ah khamriga?

RCT-da 3-usbuuc ah oo uu sameeyay Machadka Qaranka ee Xad-gudubka Khamriga iyo Khamriga ayaa ogaaday in cuntada ketogenic ay yarayn karto baahida daawooyinka sunta ah, hoos u dhigista calaamadaha khamriga, iyo yaraynta khamriga. Cilmi-baadhayaashu waxay sidoo kale ogaadeen in sawirada maskaxda ee ka qaybgalayaasha isticmaalaya cuntada ketogenic ay hoos u dhigtay bararka oo ay isbeddel wanaagsan ku yeesheen dheef-shiid kiimikaadka maskaxda.

Hordhac

In boostada blog, waxaan ahay ma si aan u qeexo calaamadaha ama heerka baahsanaanta khamriga. Boostada looguma talagalin inay noqoto mid lagu baaro ama waxbarasho habkaas ah. Waxa aan samayn doono ayaa kuu sheegi doona daraasad heer sare ah oo aad loo sameeyay oo la isticmaalayo cuntada ketogenic sida daaweynta khamriga dabadheeraad ah. Oo waxaan markaas ka wada hadli doonaa waxa hababka aasaasiga ah ee daaweynta iyadoo la adeegsanayo cunto ketogenic ah ay ku saleysnaan karto wixii horeba uga jiray suugaanta cilmi-baarista.

Cunnada ketogenic waxay daawaysaa calaamadaha ka-goynta khamriga ee bini'aadamka

Machadka Qaranka ee Xad-gudubka Khamriga iyo Khamriga ayaa sameeyay daraasad 3 toddobaad ah oo bukaan-jiif ah raagay khamriga. Ka qaybqaatayaasha waxa la dhigay qaybta cisbitaalka waana laga saaray. Kadibna si aan kala sooc lahayn ayaa loo qoondeeyay mid ka mid ah cuntada caadiga ah ee Maraykanka ama cuntada ketogenic si loo arko haddii ay isbeddel samayn karto.

Waxay ogaadeen in kuwa helay cuntada keto ay u baahan yihiin daawo sun-saar yar ah (tusaale, benzodiazepines), calaamado yar oo khamriga ah, rabitaanka khamriga oo yar, iyo baaritaannada maskaxdooda ayaa muujiyay hoos u dhaca caabuqa iyo isbeddelada dheef-shiid kiimikaadka maskaxda. (Waxaad akhrin kartaa daraasadda halkan.)

Sida haddii natiijooyinkaas aysan ahayn kuwo ku filan, waxaa jiray cudud xayawaan ah oo cilmi-baaris ah oo muujisay in jiirarka la siiyay cuntada ketogenic ay hoos u dhigtay isticmaalka khamriga.

Dadku waxay ku wareersan yihiin sida cuntada ketogenic ay u caawin karto dadka khamriga ah ee daba-dheeraada (hardcore), ee aan joojin karin cabbitaanka, burburiya noloshooda, cilaaqaadkooda, iyo jirkooda. Sidee faragelinta cuntada sida cuntada ketogenic u caawin kartaa heerkan?

Maxay noqon karaan qaar ka mid ah hababka daawaynta ee hoose?

Aynu codsano qaar ka mid ah waxa aan horeba uga naqaanay sida cuntada ketogenic ay u caawin karto daawaynta jirrooyinka dhimirka ee qoraalada hore ee blog.

Maxay yihiin arrimaha neurobiological ee aan ku aragno khamriga daba dheeraaday?

In hore post, waxaanu ka wada hadalnay hababka ay cuntada ketogenic wax uga beddeli karto calaamadaha walaaca. Qoraal kale, waxaan kaga hadalnay sida loo daweyn karo niyad-jabka. Maqaalkan waxaan ku arki doonaa in isla afartan meelood ee pathology lagu arkay khamriga:

  • Glucose Hypometabolism
  • Isku dheelitir la'aanta Neerfaha
  • caabuq
  • murqo-

Khamriga iyo Glucose Hypometabolism

Hypometabolism Glucose si fiican ayaa loo aasaasay sida habka pathological ee khamriga. Waxaan ku aragnaa hypometabolism ee wareegga hore-cerebellar iyo wareegga Papez iyo gudaha dorsolateral, premotor, iyo parietal cortices. Marka maskaxdu ay si fiican u isticmaali weydo shidaalka waxaan inta badan aragnaa hoos u dhac ku yimaada dhismayaasha maskaxda. Hoos u dhaca dhismayaasha maskaxda waa natiijada hypometabolism maskaxda ee muddada dheer. Maskaxda khamriga waxaynu ku aragnaa hoos u dhac ba'an ee dhismayaasha maskaxda ee soo socda:

  • cerebellum (dheellitirka, booska, barashada dhaqdhaqaaqa, dhaqdhaqaaqa dhaqdhaqaaqa)
  • xingulate kortex (xakamaynta fulinta, xusuusta shaqada, iyo barashada; xudunta isku xidha shucuurta, dareenka, iyo ficilka)
  • thalamus (hawlo dhowr ah, oo ay ku jiraan laxanka Circadian)
  • hippocampus (xusuusta)

Marka qof uu yahay aalkolo dabadheeraad ah, isha shidaalka maskaxdoodu waxay ka beddeshaa isticmaalka ugu horrayn gulukoosta shidaal ahaan wax loo yaqaan acetate.

Waxaa la ogaadey in isha ugu weyn ee acetate ee jirka ay ka timaaddo burburka khamriga ee beerka, taas oo keenta in si degdeg ah loo kordhiyo acetate dhiigga.

https://www.news-medical.net/news/20191024/Acetate-derived-from-alcohol-metabolism-directly-influences-epigenetic-regulation-in-the-brain.aspx

Sidee cuntada ketogenic u daawaynaysaa gulukooska hypometabolism ee khamriga dabadheeraad ah?

Acetate looma baahna in laga sameeyo khamriga lagu jajabiyo beerka. Sidoo kale waa mid ka mid ah saddexda jirka ketone ee lagu sameeyo ketosis. Iyo sidoo kale maskaxda khamriga, oo leh gulukoos hypometabolism halis ah oo ku tiirsan acetate shidaalka, waxay macno samaynaysaa in cuntada ketogenic ay bixiso badbaadinta tamarta hypometabolism-ka aan ku aragno dadkan.

Waxaan u sababeynay in ka gudubka degdega ah ee maskaxda ee isticmaalka jirka ketone, kaas oo ku dhaca Isticmaalka Khamriga (AUD) sida la qabsiga qaadashada khamriga ee soo noqnoqda, isticmaalka gulukooska sida isha tamarta, taas oo dib u soo celinaysa sunta, ay gacan ka geysan karto khamriga xanuunka ka bixitaanka.

https://www.science.org/doi/abs/10.1126/sciadv.abf6780

Si kale haddii loo dhigo, haddii maskaxdaada loo isticmaalo hal shidaal (acetate) ka dibna aad gebi ahaanba ka baxdo isha shidaalka ay doorbidayso, waxay macno samaynaysaa in rabitaankaaga shidaalkaas uu kordhin doono. In dhibaato xagga tamarta ahi ay maskaxda ka dhacdo. Laakiin haddii aad si kale u beddesho shidaalkaas, taas oo aan baabi'in jidhkaaga iyo maskaxdaada, iyada oo loo marayo cuntada ketogenic, maskaxdaadu waxay helaysaa shidaal inta jidhkaaga iyo maskaxdaadu ay qabanayaan shaqada adag ee bogsashada. Ugu dambeyntiina, sida caafimaadka dheef-shiid kiimikaadka maskaxdaada iyo jidhkaagu u fiicnaado, maskaxdaadu waxay awood u yeelan kartaa inay si fiican u isticmaasho gulukooska substrate ahaan. Laakiin ilaa ay taasi dhacdo, waxaad u baahan tahay shidaal samatabbixin ah oo la mid ah. Iyo cuntada ketogenic waxay bixisaa taas.

Khamriga iyo Isku-dheellitir la'aanta Neurotransmitter

Isku dheelitir la'aanta neurotransmitter-ka qaarkood ee lagu arko khamriga waxaa ka mid ah dopamine, serotonin, glutamate, iyo GABA.

Dopamine-ku waxay sii hurisaa dhiirigelintayada waxayna leedahay hawlo muhiim ah xarumaha abaal-marinta. Waxaa loo arkaa inay door ku leedahay sakhradda degdega ah labadaba waxayna kordhisaa si fudud marka la filayo qaadashada khamriga. Marka ay dadku maraan ka-noqoshada khamriga waxaa hoos u dhacaya shaqada dopamine, taas oo gacan ka geysan karta calaamadaha ka-noqoshada iyo soo noqoshada khamriga.

Maskaxda khamriga waxaa loo arkaa inay ka dhammaatay serotonin, waxaana loo maleynayaa in tani ay gacan ka geysaneyso dabeecadaha ku xeeran niyad-jabka iyo cabitaanka khamriga.

Isticmaalka khamriga waxay kordhisaa dhaqdhaqaaqa GABA. GABA waa neurotransmitter-ka-hortagga ah oo aan inta badan rabno in yar oo dheeraad ah sababtoo ah waxay naga dhigtaa nasasho. Laakiin maskaxda aalkolada leh, marka ay ka baxayaan, GABA waa la dejiyaa, taasoo la macno ah inaadan ka bixin karin wax ku filan.

Hababka GABA ee maskaxda ayaa lagu beddelaa xaaladaha soo-gaadhista aalkolada daba-dheeraatay. Tusaale ahaan, gobollada maskaxda qaarkood, muujinta hiddo-wadaha ee qeexaya qaybaha GABAA ee soo-dhoweynta ayaa saameeya khamriga.

Banerjee, N. (2014). Neurotransmitters ee khamriga: Dib-u-eegis ku saabsan cilmi-baarista neurobiological iyo genetic. https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4065474/

Receptors-yadu waa hawl-gab ka yihiin isticmaalka khamriga ee daba-dheeraaday. Tani waa sababta aan inta badan u siino benzodiazepines si ay uga caawiyaan ka-noqoshada dadka isku dayaya inay ka fogaadaan. Waa isku day lagu doonayo in si ku meel gaar ah loo saxo dheelitir la'aanta neurotransmitter ee ka timaadda ka-noqoshada.

Dhanka kale, glutamate waa la dejiyaa inta lagu jiro isticmaalka khamriga. Qoraalada kale ee ku saabsan xanuunada kale, gaar ahaan xanuunka welwelka, waxaan ku aragnaa glutamate oo xukuma gobolka neurotransmitter. Tani waxay noqon kartaa sababta ay dad badani is-daaweeyaan xanuunka welwelka iyagoo isticmaalaya aalkolo (tusaale walaac bulsho). Maskaxda khamriga, glutamate waxaa loo maleynayaa inay gacan ka geysato dib u habeynta maskaxda taas oo abuurta hyperexcitability iyo rabitaan inta lagu jiro khamriga.

Sidee cunnada ketogenic u caawin lahayd daawaynta isku dheelitir la'aanta neurotransmitter ee lagu arkay khamriga daba dheeraaday?

Cuntooyinka ketogenic waxay hagaajiyaan soo saarista neurotransmitters dhowr ah oo loogu talagalay maskaxda khamriga iyada oo loo marayo ka bixitaanka. Cuntooyinka ketogenic ayaa lagu muujiyey inay kordhiyaan wax soo saarka serotonin, kordhiyaan GABA, dheelitirka heerarka glutamate iyo heerarka dopamine.

Mid ka mid ah siyaabaha tan lagu dhammeeyo waa bararka oo yaraada, taas oo aan kaga hadli doono qaybta xigta. Marka maskaxdu ay la ildaran tahay xanuunka neuroinflammation (spoiler: maskaxda aalkolada hubaal waxay leedahay barar) waxay carqaladeysaa dheellitirka iyo hawlaha neurotransmitters. Qaab kale oo khamriga dabadheeraadku u carqaladayn karo dheelitirka neurotransmitter waa nafaqo-xumo. Fiitamiinada B, magnesium, iyo dhawr kale oo muhiim ah oo ka mid ah isku-xidhayaasha nafaqeeyayaalka yar yar waa ay dhammaadeen oo si fudud looma soo celiyo. Khamrigu waxa laga yaabaa in aanay mudnaanta siin cunto caafimaad leh, xitaa haddii ay sameeyaan waxa jira isbeddello ku dhaca microbiome-ka mindhicirka kaas oo yarayn kara nuugista fiitamiinnada iyo macdanta muhiimka ah. La'aanta qaadashada amino acid-ka ee ka dhalatay doorashada khamriga ee cuntada nafaqada leh waxay carqaladayn kartaa awoodda maskaxda si ay u abuurto neurotransmitters waxayna soo saartaa enzymes nidaamiya shaqada neurotransmitter.

Khamriga iyo Neuroinflammation

Neuroinflammation wuxuu dhacaa marka uu jiro wax weerar ah oo ku dhaca neerfaha. Tani waxay noqon kartaa dhaawac madaxa ah, maaddooyinka ka gudbaya xannibaadda dhiigga-maskaxda oo dareere ah, ama isticmaalka khamriga ee joogtada ah. Caabuqani, marka uu gacanta ka baxo, wuxuu keeni doonaa dhimashada unugyada, badanaaba midba midka kale. Unugyadani way bararaan oo mashiinada unugga gudaha ayaa jaba. Ugu dambayntii, unugyadan sida aan laga soo kabsan karin uga dhaawacan caabuqa, way dillaaci doonaan oo ku daadin doonaan qashinka meel aanay ka tirsanayn. Tani ma aha habka dhimashada unugyada caadiga ah ama caafimaadka qaba. Markaa burburku wuxuu markaa u horseedi doonaa geedi socod barar maxalli ah sida jidhku isku dayayo inuu nadiifiyo wasakhda.

Waxaa jira saameyn gaar ah oo khamriga (aka ethanol) uu ku leeyahay maskaxda taasoo kicisa neuroinflammation.

Nidaamka neuroimmune ee ka jawaabaya qaadashada ethanol, ee gobollada maskaxda ee gaarka ah sida amygdala, hippocampus iyo kiliyaha hore [jiirarka], waxay ku lug leeyihiin qabatinka iyo cilladaha dabeecadda ee lagu arkay khamriga.

Haorah, J., Knipe, B., Leibhart, J., Ghorpade, A., & Persidsky, Y. (2005). Cadaadiska oksaydhiyaha ee alkohol-ku-abuuray ee unugyada xuubka maskaxda ayaa sababa hawl-xumada xannibaadda maskaxda ee dhiigga. http://dx.doi.org/10.14748/bmr.v28.4451.

Neurodegeneration ee lagu arko xadgudubka khamriga dabadheeraadku wuxuu ka yimaadaa neuroinflammation dabadheeraad ah. Jawaabta neerfaha waxaa sabab u ah calaamadaynta unugyada glial (TLR4) kuwaas oo bilaabay qaabkan dhimashada unugyada.

Sidee cuntada ketogenic u yaraynaysaa neerfaha kuwa qaba khamriga dabadheeraad ah?

Cunto ketogenic ah ayaa lagu muujiyey inay si gaar ah u yareyso cytokines TLR4, iyo sidoo kale nidaaminta habka bararka. Tani waxay ku samaynaysaa iyadoo ah unug calaamadeeynaya oo awood u leh inuu shido oo damiyo hiddo-wadaha si loo dheellitiro bararka. Tani waxay hoos u dhigtaa bararka. Maskaxdana ay la kulantay khamriga daba-dheeraada waa mid gubanaysa.

Cuntooyinka ketogenic waxay kaa caawin karaan inay si dhakhso ah u yareeyaan bararka, hagaajinta awoodda maskaxda si ay u hagaajiyaan, u soo celiyaan oo u bogsadaan. Sida aan ku baranay qaybta dheelitirka neurotransmitter, caabuqu waa inuu hoos u dhacaa si neurotransmitters loo sameeyo qadar sax ah oo dheellitiran.

Xuubabka neerfaha, oo ah qayb muhiim ah oo ka mid ah unugyada maskaxda, si fiican uma shaqayn karaan haddii ay bararaan oo ay la tacaalayaan dhimashada unugyada soo socda. In bararka hoos loogu dhigo faragelin xoog leh oo ka-hortagga caabuqa, sida cuntada ketogenic, waxay noqon kartaa oo keliya faa'iido. Ka qaybgalayaasha daraasadda waxay la kulmeen barar aad uga yar marka loo eego kooxda xakamaynta iyo dhimista bararka ayaa laga yaabaa inay tahay waxa ka caawiyay ka qaybgalayaasha daraasaddan inay helaan natiijooyin wanaagsan markii ay soo mareen khamriga.

Khamriga iyo Cadaadiska Oxidative

Heerarka daran ee cadaadiska oksaydhisku waxay ku dhacaan khamriga. Cadaadiska Oxidative waxa loola jeedaa culayska yimaada marka awoodda jidhku u leeyahay in uu wax ka qabto noocyada ogsijiinta fal-celiska ah (ROS) ay ka baxayso dheellitirnaanta. Dadka aan cabin khamriga waxay abuuraan xaddi go'an oo ah noocyada ogsijiinta falcelinta oo kaliya neefsashada iyo abuurista tamar iyo inay noolaadaan. Laakiin shakhsiyaadka caafimaadka qaba, culeyskan caadiga ah ee ROS si wanaagsan ayaa loo maareeyay oo uma eka inuu wax ku biiriyo xaaladaha cudurrada ba'an (inkasta oo aan wali da'no, nasiib darro). Sida aad qiyaasi karto, khamriga daba-dheeraada waxay ku taliyaan dheelitirkan si ROS loo kordhiyo.

Cadaadiska oksaydhjiifka oo yaraada ayaa qof walba u roon, laakiin waxay si gaar ah ugu fiican tahay khamriga. Waa maxay sababtu? Sababtoo ah alkoholku wuxuu si gaar ah ugu fiican yahay inuu waxyeeleeyo xannibaadda dhiigga iyo maskaxda.

Sidaa daraadeed, diiqada oksaydhka ee ka dhalata dheef-shiid kiimikaad ee maskaxda ee unugyada xuubka maskaxda ee microvascular waxay u horseedi kartaa burburka xannibaadda dhiigga-maskaxda ee xadgudubka khamriga, taas oo u adeegta arrin sii xumaynaysa xanuunka neerfaha.

Abbott, NJ, Patabendige, AA, Dolman, DE, Yusof, SR, & Begley, DJ (2010). Qaab dhismeedka iyo shaqada xannibaadda dhiigga-maskaxda.  https://doi.org/10.1189/jlb.0605340

Caqabadda maskaxda iyo dhiigga ayaa muhiim u ah shaqada maskaxda ee caafimaadka qabta. Waa ka-hortagga weerarada ay maskaxdu ku tiirsan tahay, iyo marka isgoysyada cidhiidhiga ah ay dabacsanaadaan oo ay u oggolaadaan walxaha iyada oo aan noqon doonin, waxay keentaa jawaab-celin neuroinflammatory ah oo khatar ah. Jawaabaha neerfaha ee aan joogsiga lahayn ee joogtada ah waxay baabi'iyaan nafaqooyinka isku dayaya inay la dagaallamaan iyaga, qarxiyaan unugyada, waxayna keenaan cytokines bararka si ay u kordhiyaan caabuqa. Marka noocyada oksijiinta firfircooni ay kor u kacdo awoodda jidhku u leeyahay in uu wax ka qabto waxay hoos u dhacdaa, taas oo keenta korodhka cadaadiska oksaydhka.

Khamrigu waxay leeyihiin culays badan oo oksaydhjiif ah oo maskaxda ku jira, laakiin sidoo kale waxay ku leeyihiin jidhkooda. Cudurka beerka dufanka leh ee alkohol, habka cudur ba'an ee ku dhaca khamriga dabadheeraad ah, ayaa loo arkaa inuu abuuro xaddi badan oo cadaadis oksaydh ah.

Daaweynta ethanol ee ba'an iyo daba-dheeraatay waxay kordhisaa wax soo saarka ROS, waxay hoos u dhigtaa heerarka antioxidant-ka gacanta, waxayna xoojisaa diiqada oksaydhka ee unugyo badan, gaar ahaan beerka.

Wu, D., & Cederbaum, AI (2009, May). Cadaadiska Oxidative iyo cudurka beerka ee khamriga. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0029-1214370

Sidee bay cuntada ketogenic u yarayn kartaa walbahaarka oksaydhka ee kuwa qaba khamriga?

Cuntooyinka ketogenic waxay hoos u dhigaan cadaadiska oksaydhka siyaabo dhowr ah, qaar ka mid ah kuwaas oo aan horay uga hadalnay qaybihii hore. Cytokines bararka yar ayaa keena bararka oo yaraada waxayna abuuraan noocyo oksijiin ah oo firfircoon si loo dhexdhexaadiyo. Mid ka mid ah siyaabaha ay sidaas u sameyso waa in ay kor u qaaddo (in badan ka sameyso) endogenous (oo lagu sameeyay jirkeena) anti-oxidant oo loo yaqaan glutathione. Kani waa anti-oxidant aad u awood badan oo aad wax badan ka heshid cuntada ketogenic.

Dheef-shiid kiimikaad ee ketones-ka ayaa la muujiyey inuu hagaajiyo tamarta gacanta, kordhinta waxqabadka glutathione peroxidase, yaraynta dhimashada unugyada wuxuuna leeyahay awood ka-hortagga bararka iyo antioxidant-ka labadaba. ku jira fitamiin iyo in vivo moodooyinka.

Greco, T., Glenn, TC, Hovda, DA, & Prins, ML (2016). Cunnada ketogenic waxay hoos u dhigtaa cadaadiska oksaydhka waxayna wanaajisaa dhaqdhaqaaqa kakan ee neef-mareenka ee mitochondrial. https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC5012517/

Ketones-ku waxay tan sameeyaan iyagoo kordhinaya wax unugyadu runtii u baahan yihiin oo lagu yarayn karo cudurrada daba-dheeraada sida khamriga. Shaygan muhiimka ah waxaa loo yaqaan nicotinamide adenine dinucleotide phosphate hydrogen (NADPH) waxaadna uga fikiri kartaa sidii wax wada-qabsi ah, taasoo la macno ah unugyadu waxay u baahan yihiin si ay wax u qabtaan. Wax badan oo ka mid ah isbahaysigan ayaa ka caawiya jidhkaaga inuu isticmaalo enzymes si uu u dhaqaajiyo antioxidants xoogga leh ee jirkaaga, sida glutathione.

Siyaabaha kale ee cuntada ketogenic ay u wanaajiso walbahaarka oksaydhisku waa shaqada xuubabka unugga ee la hagaajiyay ee aan mar hore dib u eegnay. Shaqadan xuubabka unugga ee la wanaajiyey waxay keentaa nidaaminta synaptik, abuurista dheellitirnaanta neerfayaasha. Korodhka mitochondria, xarumaha tamarta ee unugyada neerfayaasha, ayaa siiya unuggu tamar badan si uu u hagaajiyo calaamadaha unugyada iyo tamar ku filan si uu u nadiifiyo loona ilaaliyo unugyada iyo dhammaan qaybihiisa.

Ugu Dambeyn

Cunnada ketogenic maaha kaliya daawaynta aragtida ee cilladda isticmaalka khamriga. Waxaan rajeynayaa in dadku ay isticmaali doonaan faragelintan cunto iyo nafaqeynta ee xoogga leh si ay uga caawiyaan socdaalkooda soo kabashada. Gaar ahaan kuwa u halgamay ama ku guul daraystay waagii hore iyagoo isticmaalaya heerka daawaynta ee hadda jirta.

Iyada oo la kaashanayo sun-saarista caafimaad ahaan la kormeero, cuntada ketogenic waxay daawaysaa khamriga waxayna u badan tahay, sida laga soo xigtay qaybta daraasadda xayawaanka ee cilmi-baaristan, waxay gacan ka geysataa suurtagalnimada ka hortagga soo noqoshada.

Waxaan rabaa inaan kugu dhiirigeliyo inaad wax badan ka barato doorashooyinkaaga daawaynta mid ka mid ah kuwan soo socda posts blog. Waxaan wax uga qoraa habab kala duwan siyaalo kala duwan oo tafatiran oo laga yaabo inaad ku caawiso inaad wax ka barato safarkaaga fayoobida. Waxaa laga yaabaa inaad ku raaxaysato Daraasadaha Kiis Ketogenic bogga si aad u barato sida dadka kale u isticmaaleen cuntada ketogenic si ay u daweeyaan jirrooyinka dhimirka ee shaqadayda. Waxaana laga yaabaa inaad ka faa'iidaysato fahamka sida la shaqaynta lataliyaha caafimaadka dhimirka markaad u gudbayso cuntada ketogenic ay waxtar u yeelan karto halkan.

La wadaag qoraalkan baloogga ah ama kuwa kale asxaabta iyo qoyska la ildaran xanuunka dhimirka. Dadku ha ogaadaan inay rajo jirto.

Wax badan oo aniga igu saabsan ayaad baran kartaa halkan. Haddii aad rabto inaad ila soo xidhiidho waad samayn kartaa halkan. Sharaf ayey ii tahay inaan kuu sheego dhammaan siyaabaha kala duwan ee aad ku dareemi karto fiicnaan.

Ma jeceshahay waxa aad ka akhrinayso blog-ka? Ma doonaysaa inaad wax ka barato webinars soo socda, koorsooyin, iyo xataa waxay bixisaa taageero iyo ila shaqaynta xagga yoolalkaaga fayoobi? Isdiiwaangeli!


tixraacyada

Acetate oo ka soo jeeda dheef-shiid kiimikaadka khamriga ayaa si toos ah u saameeya nidaamka epigenetic ee maskaxda. (2019, Oktoobar 24). News-Medical.Net. https://www.news-medical.net/news/20191024/Acetate-derived-from-alcohol-metabolism-directly-influences-epigenetic-regulation-in-the-brain.aspx

Banerjee, N. (2014). Neurotransmitters ee khamriga: Dib-u-eegis ku saabsan cilmi-baarista neurobiological iyo genetic. Wargeyska Hindiga ee Hiddaha Aadamaha, 20(1), 20. https://doi.org/10.4103/0971-6866.132750

Castro, AI, Gomez-Arbelaez, D., Crujeiras, AB, Granero, R., Aguera, Z., Jimenez-Murcia, S., Sajoux, I., Lopez-Jaramillo, P., Fernandez-Aranda, F. , & Casanueva, FF (2018). Saamaynta Cunnooyinka Ketogenic-ka ee aadka u hooseeya ee Cunnada iyo Khamriga rabitaanka, Jirka iyo Dhaqdhaqaaqa Galmada, Hurdada Hurdada, iyo tayada nolosha ee Bukaannada buuran. Nafaqooyinka, 10(10), 1348. https://doi.org/10.3390/nu10101348

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